Hot pot with milk tea, turn Tuesday into weekend! It is so difficult for modern people to resist the troubles of food. They accidentally eat "happy fat", followed by the troubles of body shape and three heights.

When we are seeking to create the perfect diet, carbohydrates are often cited as the culprit for a good healthy diet. Carbohydrates are widely regarded as a source of food energy for humans or animals. This energy comes from the increased metabolism caused by eating carbohydrates. Carbohydrates, including starch, sugar, cellulose and sugar gums.

It has two forms, simple and complex carbohydrates. Simple carbohydrates are found in foods, such as candies, fruits, and baked foods; complex carbohydrates can be found in starchy foods, such as beans, whole grains, and nuts. The types of carbohydrates in the diet may affect cardiometabolic risk by changing the intestinal flora and its derived metabolites.

Carbohydrates can regulate the health of the body by affecting the intestinal flora. At the same time, the intestinal flora can participate in the metabolism of the body by fermenting carbohydrates to produce short-chain fatty acids. The two are interrelated and affect each other. The following is the number of research papers on intestinal flora and carbohydrates in the SCI database in the past 20 years.

Number of related papers published in the SCI database (2000-2019)

In the past 20 years, the number of research papers related to'intestinal flora and carbohydrates' in the SCI database has been only more than ten

By 2019, there were more than 400 articles, an increase of dozens of times.

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Establish a healthy diet

What kind of food will become a "unicorn" in the field of sports and health

As people pay more and more attention to healthy eating, people with diabetes and those who desire to control their weight have avoided high-carbohydrate foods. People hope to control body shape through low-carb water diet and prevent diabetes, cardiovascular disease and a series of complications. However, most people do not have adequate knowledge of diet control.

Take food as an example. Is it true that foods with high sugar content cannot be eaten, and foods with low sugar content can be eaten more? This is not the case. Today, scientists even recommend using the glycemic index (GI) to assess the effect of food on blood sugar levels. The glycemic index indicates the percentage value of the blood glucose response level in the body within a certain period of time (usually 2 hours after a meal) of a food containing 50g of valuable carbohydrates compared with a comparable amount of glucose. After high GI food enters the gastrointestinal tract, digestion is fast, the absorption rate is high, and glucose enters the blood quickly, causing high blood sugar peaks; while low GI foods are the opposite.

Many low-carbon water foods have emerged in the market, such as sugar-substituted yogurt, zero-sugar beverages, and baked goods. However, many diets still contain carbohydrates, so we need to understand the digestion and absorption pathways of carbohydrates in the body to find substances that can inhibit carbohydrate absorption. For this demand, we found a probiotic, Lactobacillus plantarum grx16.

Carbon water blocking under great health

Lactobacillus plantarum grx16

01-About Lactobacillus plantarum grx16

Lactobacillus plantarum grx16 (Lactobacillus plantarum grx16) was isolated and screened from the intestines of long-lived people in Bama, Guangxi by the team of Professor Gu Ruixia of Yangzhou University.

The team separated and purified a large number of samples collected in Bama, Guangxi, and initially obtained 180 strains of lactic acid bacteria; secondly, after a series of screenings, one strain was obtained with strong inhibitory ability to α-glucosidase, and has the ability to tolerate acid and bile salts, and to resist in vitro. The lactic acid bacteria strain grx16 with oxidizing ability and sensitive to a variety of antibiotics.

This strain can be used in fermented dairy products, dietary supplements and other products.

Then let's take a look at this strain of Lactobacillus plantarum grx16.

In 2015, the deposit number of the strains declared for preservation: CGMCC NO.10921

In 2015, it declared a Chinese invention patent, patent number: ZL 2015 1 0551144.0

Patent name: Lactobacillus plantarum Grx16 and its application

In 2015, it declared a Chinese invention patent, patent number: ZL 2015 1 0553213.1

Patent name A method for preparing high-quality fermented camel milk with auxiliary function of lowering blood sugar

02-Overview of the efficacy of Lactobacillus plantarum grx16

Digestion of carbohydrates starts in the mouth, and some carbohydrates are initially digested by salivary amylase; carbohydrates are almost completely digested in the stomach; in the small intestine, digestion in the small intestine is divided into intestinal cavity digestion and small intestinal mucosal epithelial cell surface Digestion.

The main site of carbohydrate metabolism and digestion is in the small intestine. The final product is glucose and a small amount of fructose and galactose. Among them, the important hydrolase is α-glucosidase. Inhibiting the activity of α-glucosidase can slow down the hydrolysis of carbohydrates to generate monosaccharides (such as glucose) and delay their absorption, thereby reducing postprandial blood glucose peaks and blood glucose fluctuations, and there is a tendency to reduce weight.

The colon and small intestine are the places where probiotics adhere to and colonize. Therefore, GRX16, which has α-glucosidase inhibitory ability, can inhibit the hydrolysis of starch or maltose into glucose in the intestine, and block the body's absorption of carbohydrates.

03-Efficacy verification of Lactobacillus plantarum grx16

Lactic acid bacteria were isolated from the intestines of long-lived people in Bama, Guangxi. Based on the comprehensive comparison of acid resistance and bile salt resistance, in vitro antioxidant capacity, and sensitivity to antibiotics, a strain was screened out to inhibit α-glucosidase activity through in vitro tests. The most capable strain.

By screening out lactic acid bacteria with excellent ability to inhibit α-glucosidase in vitro, the lactic acid bacteria can be used to prepare functional foods with functions of regulating blood sugar and promoting body health.

The specific experimental data are as follows:

[Grx16 acid and bile salt resistance test]

The results showed that the rates of Grx16 resistance to gastric juice, bile salt and intestinal juice reached 68.80%, 38.48%, and 35.30%, respectively.

【Grx16 Antioxidant Capability Test】

The 25 strains of lactic acid bacteria fermentation broths all have a certain scavenging ability for DPPH free radicals, with a scavenging rate of 25% to 82%. Among them, grx16 has a strong ability to scavenger DPPH free radicals, which is 81.16%. The reducing ability is between 0.7 and 2.8, and the strain grx16 has the strongest reducing ability.

[Grx16 α-glucosidase inhibitory ability]

The strain grx16 has a high inhibitory activity on α-glucosidase, with an inhibition rate of 89.47%.

04-Study on the application of Lactobacillus plantarum grx16

The following is the relevant experimental data of Lactobacillus plantarum grx16 combined with other strains as a starter to ferment camel milk.

[Effects of probiotics fermented camel milk on the organ index of diabetic rats]

The organ index of the intervention group was significantly lower than that of the model group (P<0.05). In general, the organ index from low to high was the normal group, the drug group, the camel fermented milk group, the camel milk group, and the model group. It shows that fermented camel milk can protect the main organs of diabetic rats to a certain extent, and it has positive significance for assisting the treatment of diabetes.

[Effects of probiotic fermented camel milk on fasting blood glucose (FBG) in diabetic rats]

The blood glucose control ability of fermented camel milk is stronger than that of camel milk. Compared with the first week, the blood sugar concentration of the camel milk group decreased by 17.87%, while the blood sugar concentration of the camel milk group was decreased by 16.81% compared with the first week, and compared with the model group The difference is significant (P<0.05).

It shows that after a certain period of intervention, both camel milk and fermented camel milk have a strong ability to assist in lowering blood sugar, but camel milk takes longer.

【Effect of Probiotics Fermented Camel Milk on Glucose Tolerance (OGTT) in Diabetic Rats】

It can be seen from the figure that after 4 weeks of intervention, both the camel milk group and the fermented camel milk group have a certain effect on improving the sugar tolerance of rats, while the fermented camel milk group has a better effect.

After 2 hours of intragastric administration, the blood glucose level had decreased to 17.82mmol/L, which was significantly different from the model group.

It shows that fermented camel milk has the effect of improving OGTT in rats.

05-Study on the application of Lactobacillus plantarum grx16

Lactobacillus plantarum grx16 can be used in beverages, dairy products and other foods, and can give products more reliable functional characteristics.

The patented Lactobacillus plantarum grx16 can be used in beverages, yogurt, zero dietary supplements and other products. It not only imparts functionality to the product, but also protects the effect of the product.

At present, dietary supplement products and dairy products related to Lactobacillus plantarum grx16 have been developed.

At the same time, we are opening up more possibilities for Lactobacillus plantarum grx16.

Lactobacillus plantarum grx16 powder

Number of viable bacteria: 1×10^11 CFU/g,

Packing specification: 10D/bag, 1kg/bag, or customized

Storage conditions: Store at -18℃

If you want to know more product information, please contact your business manager, we will answer for you as soon as possible.